The vineyards of Château Troplong Mondot were originally part of the Pavie estate, but became a separate entity in 1850, when they were acquired by Raymond Troplong.   The pretty little château itself was built in 1745.  The estate passed through various hands until it was bought by the Valette family in the 1930s.  Troplong Mondot's modern history began in 1980, when Christine Valette took over the running of the estate, introducing many of the fundamentals of making high quality Bordeaux such as hand-harvesting, reducing yields, increasing the use of new oak and vinifying parcel by parcel.  The estate quickly became a leading light of new wave St-Emilions.

Christine Valette passed away in 2014 and her relative Xavier Parente took over, bringing in Aymeric de Gironde (formerly of Cos d'Estournel) as winemaker.  In 2017 the property was sold to a French insurance company SOCR, who invested in new cellars.  Aymeric de Gironde has set about taking Troplong Mondot in a new direction, with less new oak and a fresher, more terroir-driven style.