Château La Mission Haut-Brion is a Grand Cru Classé de Graves estate in the communes of Pessac-Léognan.  The estate dates to the 16th century, when it was first purchased by Jean de Pontac in 1533, shortly after Haut-Brion itself came into his ownership by marriage.  It subsequently passed out of the Pontac family and from 1664 was owned by the Catholic Church, in particular the monastic order of the Lazarite brothers of the Prêcheurs de la Mission, who continued to make the wine, very adeptly. 

In 1698, a small chapel was built, known as Notre Dame de La Mission.  The actual château was built in 1713.  After the French Revolution, it passed again from the Church to private hands and was owned until 1983 by the Woltner family.  Since that time it has been part of Domaines Dillons.

in the nineteenth century La Mission was regarded almost as highly as the First Growths, but was not included in the 1855 Classification (Haut-Brion itself was the only non-Left Bank wine included).

The 30.7-hectare vineyard has 27 hectares planted for red wine grapes and 3.7 hectares reserved for white wine grape varieties. The red vineyard is planted to planted to 45.8% Cabernet Sauvignon, 43.8% Merlot and 10.4% Cabernet Franc. The white wine is La Mission Haut-Brion Blanc.  A second wine is also produced, La Chapelle de la Mission Haut-Brion.